ABSTRACT
Small intestinal bacterial overgrowth (SIBO) is characterized by changes in the number or species of small intestinal flora. Patients with liver cirrhosis often have intestinal congestion, edema, and delayed peristalsis and develop SIBO, which can further aggravate intestinal abnormalities. In patients with liver cirrhosis, SIBO can lead to significant adverse clinical outcomes, and since the increase in intestinal permeability may cause bacterial translocation into systemic circulation, SIBO is considered an important risk factor in the pathogenesis of liver cirrhosis, spontaneous bacterial peritonitis, and hepatic encephalopathy. Antibiotics, especially rifaximin, are the most effective therapies for SIBO, and in addition, studies are being conducted to investigate the efficacy of potential therapies such as prokinetic agents, probiotics, non-selective β-receptor blocker, and liver transplantation.
ABSTRACT
Gastric cancer is one of the most common malignancies and is the third leading cause of cancer-related deaths worldwide, constituting a serious threat to human health. Long non-coding RNA (lncRNA) is involved in the occurrence and development of gastric cancer at multiple levels and plays critical regulatory roles. It plays important roles in the diagnosis, treatment and prognostic assessment of gastric cancer. This review focuses on the recent research advances in the clinical applications of lncRNA in gastric cancer.
ABSTRACT
BACKGROUND:Nowadays, it has become the focus of people to seek effective and feasible prevention and control methods for chronic disease. With the vigorous development of electronic information, as a new thing in the development of science and technology, mobile health (mHealth) has a great potential in the prevention and management of chronic diseases. However, the current research on mHealth is less. OBJECTIVE:To explain the mode of mHealth in the prevention and control of chronic disease, its application effects, the current status of mHealth App at home and abroad, and to make the prospect of mHealth. METHODS:We searched for the literatures related to mHealth at home and abroad, and explored its development status. We retrieved Ovid database and China National Knowledge Infrastructure for articles published until December 2015. The key words were“mHealth, Chronic disease”. RESULTS AND CONCLUSION:(1) There were 32 English articles and 19 Chinese articles. Of them, 10 articles were about mHealth. 15 articles were related to chronic disease. 26 articles explored the use of mHealth in prevention and control of chronic disease. (2) Results suggested that mHealth has a certain effect and potential in the prevention and control of chronic diseases.